Methylene cyclopropyl acetic acid

Description

Methylene cyclopropyl acetic acid (MCPA) is found in lychee seeds and is also a toxic metabolite in mammalian digestion after eating hypoglycin, present in the unripe ackee fruit, grown in Jamaica and in Africa. By blocking coenzyme A and carnitine, MPCA causes a decrease in β-oxidation of fatty acids, and hence gluconeogenesis.